levaquin iv can pass into breast milk and may harm a nursing baby allergic reaction to levaquin. levofloxacin is used treat infections such as pneumonia; chronic bronchitis; and sinus, urinary tract, kidney, and skin infections. v side effects prescription drug levaquin. other drugs which contain these ions and which can similarly interact with levofloxacin include sucralfate (carafate) and didanosine, ddi drinking alcohol with levaquin. antibiotics will not work for colds, flu, or other viral infections. the usual dose of levaquin iv tablets or oral solution (25 mg/ml) is 250 mg or 500 mg or 750 mg administered orally every 24 hours, as indicated by infection and described in the following dosing chart levaquin pneumonia. the antibacterial activity of ofloxacin resides primarily in the l-isomer. renal insufficiency: clearance of levofloxacin is reduced and plasma elimination half-life is prolonged in patients with impaired renal function (creatinine clearance ?80 ml/min), and dosage adjustment may be required in such patients to avoid accumulation drinking alcohol with levaquin. levofloxacin pharmacokinetics are linear and predictable after single and multiple i. in the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. if you have diarrhea that is watery or has blood in it, call your doctor. serious and occasionally fatal events, such as hypersensitivity and/or anaphylactic reactions, as well as some of unknown etiology have been reported in patients receiving therapy with quinolones, including levofloxacin drug effects levaquin more side. there have been reports of changes in blood sugar in patients treated with other fluoroquinolones and antidiabetic agents. the quinolone should be discontinued in patients experiencing pain, inflammation, or rupture of a tendon. the usual dose of levaquin iv injection is 250 mg or 500 mg administered by slow infusion over 60 minutes every 24 hours or 750 mg administered by slow infusion over 90 minutes every 24 hours, as indicated by infection and described in the following dosing chart. infusion of 500 mg of levofloxacin to healthy volunteers, the mean peak plasma concentration attained was 6. due to the limited extent of levofloxacin metabolism, the pharmacokinetics of levofloxacin are not expected to be affected by hepatic impairment levaquin injection. conversely, microorganisms resistant to fluoroquinolones may be susceptible to other classes of antimicrobial agents. the peak and trough plasma concentrations attained following multiple once daily i. this risk is increased in patients over 65 years old, and is further increased with concomitant corticosteroid therapy. dose adjustment based on gender alone is not necessary . levofloxacin penetrates into blister fluid levaquin tablets. therefore, the oral and i cost levaquin. the safety and efficacy of levofloxacin in pediatric patients, adolescents (under 18), pregnant women, and nursing mothers have not been established. levofloxacin binding to serum proteins is independent of the drug concentration. levofloxacin also penetrates into lung tissues. levaquin treat antibiotic. it is recommended that levofloxacin oral solution be taken 1 hour before or 2 hours after eating. g. i. antibiotic medicines can cause diarrhea, which may be a sign of a new infection. less common side effects include difficulty sleeping, dizziness, abdominal pain, rash, abdominal gas, and itching. take levaquin iv with a full glass of water (8 ounces). gender: there are no significant differences in levofloxacin pharmacokinetics between male and female subjects when the differences in creatinine clearance are taken into consideration levaquin package insert. take levofloxacin exactly as directed generic levaquin. drug absorption appears to be unaffected by age. children: the pharmacokinetics of levofloxacin in pediatric patients have not been studied. the peak and trough plasma concentrations attained following multiple once-daily oral 500 mg regimens were approximately 5. dosing regimens. the blister fluid to plasma auc ratio is approximately 1 antibiotics levaquin flagyl.